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In healthy individuals, excess copper is effectively excreted via bile, maintaining homeostasis [59]

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For most patients, the choice depends on efficacy goals and side effect tolerance rather than cardiac risk

The surge in chronic inflammatory diseases (CIDs) including infectious, allergic, neuroinflammatory, neurodegenerative, autoimmune diseases, and cancer has been extensively reported by the Human Genome Project

doi: 10.2337/db13-0396
