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Particularly concerning, it appears that some studies were either canceled or stopped without conclusions

doi: 10.1002/cbic.201700352

A systematic review (PMID: 40756949) examined its emerging use in orthopaedic sports medicine, while a 2025 pilot study (PMID: 40131143) provided early human safety data

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For patients already under investigation or treatment for known conditions, elevated B12 should be discussed with your specialist or GP at your next scheduled appointment