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The California-based company Teneobio targeted CD38 with the aim of developing an antibody capable of fully inhibiting the enzymatic activities of the moleculenot yet achieved with the anti-CD38 reagents currently used in in vivo therapy

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This paradoxical response affects some patients receiving hydroxocobalamin treatment for vitamin B12 deficiency

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doi: 10.1111/j.1365-2605.2011.01230.x
