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However, there remains a large gap to be filled in translating in vitro models to animal and human models

Given the drop in its activity at elevated temperatures or under denaturation conditions, the group employed a crosslinking strategy that uses biselectrophiles that target pairs of Cys to enhance its stability

Some articles point out that KEAP1-mutated cells have an increased dependence on glutamine, and inhibiting GLS can selectively kill these cells