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Although the main role of TRH is the stimulation of the synthesis and release of the thyroid stimulating hormone (TSH) to control the thyroid gland (192), TRH influences the secretion of other pituitary hormones (38)

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However, exogenous expression of GGT1 can inhibit GSH depletion in GGT1-deficient cells, thereby preventing the accumulation of lipid peroxidation and ferroptosis due to cystine deficiency