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Lardenoije, R

Moreover, substituting the appropriate AMP residue could help to improve their therapeutic index

With live bacteria, adhesion is an early and critical event in translocation since it anchors bacteria in place, leads to physical damage to host cells, concentrates toxins at cell surfaces, and activates cellular microbe-associated molecular pattern (MAMP) sensors [87, 88]

The role of mitochondrial DNA in mediating alveolar epithelial cell apoptosis and pulmonary fibrosis

Additional evidence of oxidative stress in MS are the presence of increased protein carbonyls, NO metabolites, SOD, catalase, glutathione reductase, inducible nitric oxide synthase (iNOS), protein carbonyl, 3-NT, isoprostanes, MDA, 8-iso-prostaglandin F2 and products of DNA oxidation in blood, serum, urine and postmortem brain of MS patients [71]