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Taking berberine with food may reduce gastrointestinal side effects and may enhance absorption

Additional file 6: Figure S4
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Janssens R, Struyf S, Proost P
The most critical advantage of this structural change is ALCAR's ability to efficiently cross the highly selective blood-brain barrier (BBB), though the cited study actually discusses the pharmacokinetics of DA-8159, a new erectogenic, in rats
