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Low tumor oxygen and low blood oxygen enhance tumor growth and create resistance to treatment as described in the section The Five Rs of Radiobiology (Gaspar 2015)

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reported that clopidogrel is an alternative antiplatelet agent that can be used in Kawasaki disease and therefore may be useful for MIC-S ( The literature highlights that the anatomopathological criterion for Reye's syndrome, with liver biopsy, may be useful, but the risk of complications, such as bleeding, is increased ( The child underwent treatment with intensive support, initially for MIC-S and, subsequently, for Reye's syndrome

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