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Nevertheless, these cell lines present some indicators of genomic drifts upon prolonged in vitro culture time, which can lead to unwanted clonal selection and genomic divergence from the initial primary tumor patients

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Relevant tests include: Total and free testosterone LH and FSH TSH, free T3, and free T4 SHBG (sex hormone binding globulin) Retesting at 4-6 weeks and again after completing a cycle provides data for evaluating response

[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Zhang H, et al