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[DOI] [PubMed] [Google Scholar] 33.Garcia S.C., Schott K., Charao M., Moro A., Bulcao R., Grotto D., Valentini J., Bohrer D., Cardoso S., Pomblum V

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To mitigate over-assignment to sorted TME cell types, we included unsorted cell types (neoplastic + oligodendrocyte precursor cell with high transcriptomic similarity) in this deconvolution step as a block effect

CURRENT UNDERSTANDING OF METABOLIC PATHWAYS INVOLVED IN FERROPTOSIS Glucose, glutamine, and fatty acids are major metabolic fuels to meet nutritional demands [16]

Interestingly, high GPX1 and GPX4 expression are correlated to poor prognosis in patients suffering AML, suggesting that targeting one or both proteins could be of high potential therapeutic value [36]