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When its missing, everything else runs poorly
J Am Coll Cardiol
B., Nowak, J., Skjaerbaek, C., Flyvbjerg, A., Andreassen, T
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296,298 One case report described the benefit of SAMe in a 32 year old patient with anxiety who was found to have a MTHFR gene mutation: treatment with methylated B 12 and folate was not effective for relieving symptoms until SAMe, 400 mg twice daily, was added
