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This observation suggests that E2 may stimulate mitochondrial ROS production, potentially influenced by the concentration of supplemental estrogen or the distribution of receptors

(Many of the heart benefits in wine, for instance, come from antioxidants that are easily found in grapes or pomegranate without the dangerous add-ons of booze.) In fact, alcohol can cause heart palpitations and sometimes lead to the so-called holiday heart syndrome if we overdo it

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