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These pathogens often exhibit intrinsic or acquired resistance to antifungal agents, severely limiting treatment options
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In our study, environmental inflammatory factors including IL-1 were significantly increased in mice subjected to social isolation stress, which is in line with previous studies that indicated that people who experience adversity early in their lives have a significant increase in CRP and IL-6 levels compared to healthy individuals 43
Such autoantibodies appear decades before clinically apparent disease (8)
