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Mitochondrial dysfunction caused by toxins further amplifies ROS generation, establishing a feedback loop that accelerates DNA damage and carcinogenic transformation [21]

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Although this issue is far from the main focus of this review, evidence on the role of oxidative/nitrosative stress in this context is emerging

DISCUSSION Any living cell produces ROS, either as a by-product of mitochondrial respiration or in a controlled manner by different oxidases to modulate cell signaling

Signs of ketamine intoxication include mood swings, delusions, hallucinations, and depression