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The irreversibility of glycolysis arises from three strongly exergonic reactions that cannot be used in gluconeogenesis
[DOI] [PubMed] [Google Scholar] 20.Husain AM, et al
3a, Methods)
In people with the familial form of PCT, a confirmed diagnosis can be made from a deficiency of UROD genes in red blood cells
Other important areas to be focused on are identifying and validating biomarkers for diagnosis and treatment monitoring and exploring novel therapeutic targets such as antioxidants and mitochondrial biogenesis stimulators
