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High doses of B12 are thought to support cellular energy production, which may provide a short-term energy boost

Comparable age groupings are proposed in the Dietary Guidelines for Americans, though the recommended intake levels differ, beginning at 0.5 g in infancy, increasing to 2.4 g for adults, and rising modestly during pregnancy and lactation (2.6 g and 2.8 g, respectively

All experiments were carried out in accordance with the Guide for the Care and Use of Laboratory Animals [20] and with approval from the Institutional Animal Care and Use Committee at the University of Texas Medical Branch

They are typically prescribed when oral supplements are ineffective or when rapid improvement of symptoms is required