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3.3 Analysis of preclinical and clinical research supporting the concept of chronotherapy in the treatment of cancer The concept of chronotherapy, which involves tailoring treatment schedules to the patients circadian rhythms, has garnered significant attention in both preclinical and clinical settings

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Although MSC-assisted islet transplantation has been widely reported in a variety of animal models, most of the research mainly focused on the effect of MSCs on alloimmunity

Noonan syndrome-causing SHP2 mutants inhibit insulin-like growth factor 1 release via growth hormone-induced ERK hyperactivation, which contributes to short stature