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Interestingly, loss of muscle mass in itself appears not to be associated with functional decline and disability [51] but rather maintenance of muscle strength is key to preventing functional decline [52], with randomised controlled trials (RCTs) demonstrating the benefit of resistance training in older adults [53]

It reported 22.7% mean weight loss at 68 weeks vs 16.1% for semaglutide alone and 11.8% for cagrilintide alone clear additive benefit

further in-depth studies are needed in the future to verify its safety and efficacy

Among these nanosytsems, polymer-based carriers, including polycaprolactone (PCL), polyethylene glycol (PEG), and chitosan, PLGA, offered an attractive biodegradable platform for encapsulating both synthetic drugs and bioactive natural compounds 29

Chinese Herbal Medicine: Modern Applications of Traditional Formulas