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Impaired acidification, fusion defects and reduced endosomeautophagosomelysosome pathway flux compromise the clearance of pathogenic aggregates, and raising cellular cAMP or free zinc has been proposed as a strategy to restore lysosomal pH and proteolytic capacity in affected neurons 166

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The ability to achieve diverse oxidative patterns is particularly interesting for chemical biology, as hydroxylated terpenes exhibit increased solubility 36

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[DOI] [PubMed] [Google Scholar] 41.Pandey A., Nikam A., Basavraj S., Mutalik S., Gopalan D., Kulkarni S., Padya B., Fernandes G., Mutalik S
