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Humans are exposed to lead via several routes: the digestive system, pulmonary system, and small amounts via the dermal route (Rdulescu and Lundgren 2019)

Once daily versus three times daily mesalazine granules in active ulcerative colitis: a double-blind, double-dummy, randomised, non-inferiority trial

Given the toxic effect of excess selenium, it should be cautious about extrapolation of current results

At this stage, the therapeutic efficacy of Rg1 remains to be established by further clinical validation, although the initial findings are encouraging

What monitoring protocol do you use for patients on this therapy