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Zhao, M

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Clinical observations in EPP patients support anti-inflammatory activity afamelanotide-treated subjects showed reduced severity of phototoxic inflammatory reactions beyond what eumelanin-mediated UV absorption alone would predict

[47] Because of this mode of spread the key groups at risk are intravenous drug users (IDUs), recipients of blood products and sometimes patients on haemodialysis

Furthermore, many novel agents also have CIPN as a dose-limiting side-effect, whether as a direct toxicity or secondary due to immune-mediated processes
