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the principal pharmacological-interaction consideration is co-administration with exogenous melatonin or other pineal-axis-modifying agents, where the proposed mechanism overlaps and pharmacodynamic addition rather than subtraction would be expected

The American Society of Anesthesiologists recommends managing patients on GLP-1 receptor agonists as if they have a full stomach, including appropriate airway protection and rapid sequence induction

Full and distended stomach, and vascular response"