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The high antioxidant activity of sesamin has been reported (Pathak et al., 2014)

10.3389/fncel.2021.615372 553 ZhangY.SwandaR

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Lower systemic inflammation can lead to clearer skin and better tone

however, a major issue has been that only 0.10.2 % of the antibodies reach the CNS (Pardridge 2019), and that they act against the extracellular spreading but are unable to penetrate the cells (Gaston et al