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The strongest published finding is from the foundational Biochemical Pharmacology study by Neelakantan et al.: in diet-induced obese mice, daily 5-Amino-1MQ administration produced reductions in body weight, white adipose tissue mass, and adipocyte size without any significant change in food intake

Despite these major changes in myelin, OLs, and A immunoreactivity, no cognitive impairment or hippocampal pathology was detected in APP/PS1 mice after cuprizone treatment

One day prior to the experiment, hair was removed from a 2 cm 3 cm area on the dorsal skin of each mouse using an electric shaver followed by depilatory cream

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10.1007/s00595-007-3706-2 52 ParkJ