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Description
The biochemical activity of the drug metabolizing isozyme cytochrome P450 2D6 (debrisoquin hydroxylase) is reduced in a subset of the Caucasian population (about 7% to 10% of Caucasians are so-called "poor metabolizers")
doi: 10.1210/jcem.83.7.4966 119 BellentaniSScaglioniFMarinoMBedogniG
Pi3k and Mapk pathways mediate the Bdnf/Trkb-increased metastasis in Neuroblastoma

doi: 10.1016/0014-5793(79)80069-1

In humans, the 48 ABC transporters are classified into seven subfamilies (A through G) according to their relative degrees of sequence homology
