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Similarly, glucose deficiency suppressed ferroptosis by inhibiting glycolysis, the TCA cycle, and fatty acid synthesis mediated via pyruvate dehydrogenase kinase 4 (PDK4) 89

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For the dose response study, Wistar rats receiving 1.5 L of FLuc mRNA-loaded pB-UC18 LNPs at different mRNA doses (40, 120, and 200 ng per injection) through IC injection were imaged at 4 h post-injection