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Interestingly, it has been shown that GSH levels tend to increase due to glutamate-mediated excitatory activity (Tebartz Van Elst et al., 2014), and one of the hypotheses related to symptoms of ASD is the presence of an imbalance between excitatory neurotransmitter, glutamate, and one of the principal inhibitory transmitter, GABA

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Thermo Fisher Scientific) in PBS for 30 min on ice

Melatonin as a potential modulator of Nrf2

3 Apart from alteration in glucose metabolism, there are compelling evidences showing that cancer cells have specific alterations in different aspects of lipid metabolism