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Biomaterials 217 , 119303 (2019)

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Neurosci Res 37:159, PMID: 10802340 Tanaka K, Watase K, Manabe T, Yamada K, Watanabe M, Takahashi K, Iwama H, Nishikawa T, Ichihara N, Kikuchi T, Okuyama S, Kawashima N, Hori S, Takimoto M, Wada K (1997) Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1

This increased susceptibility for cell death in G6PD-deficient cells can lead to adverse physiological effects under conditions of increased oxidative stress in tissues where the specific cell type is indispensable (44, 45, 48, 75, 101, 105, 111, 115)

When administered, the peptide preferentially accumulates in adipose tissue, where it interacts with beta-3 adrenergic receptors on fat cell membranes and initiates metabolic signaling cascades