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doi: 10.3389/fimmu.2022.878771 Received 18 February 2022 Accepted 20 April 2022 Published 18 May 2022 Volume 13 - 2022 Edited by Serge Nataf, Universit Claude Bernard Lyon 1, France Reviewed by Omid Mirmosayyeb, Isfahan University of Medical Sciences, Iran

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AKR1C3 also catalyzes the activation of estrone to 17-estradiol, and the inactivation of progesterone to 20-hydroxyprogesterone in the breast with consequent transactivation of the estrogen receptor [61,62]

doi: 10.3390/jof5010026 325 Prevention, E

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