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Diet strategy Caloric deficit is mandatory

Hodgson N, Gitlin LN (in press)

There is currently no established pharmacological mechanism by which tirzepatide would directly cause sleep disruption, though research in this specific area is limited

Acta Otorhinolaryngol Ital

Standard Therapeutic Cycle (12 Weeks): Clinical trials frequently employed 12-week protocols, which provide sufficient duration for measurable metabolic changes while establishing safety through comprehensive monitoring
