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Autophosphorylation at tyrosine 397 is commonly used as a marker of FAK activation because it creates a binding site for Src-family kinases and supports downstream signaling events involved in adhesion turnover and migration-associated processes
It also plays a role in the production of the myelin sheath that surrounds nerves as well as the conduction of nerve impulses
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Diagnosis and management of adult BPI: results of first 50 cases
