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Using an ad libitum energy intake model, MK-0493 was associated with a small and marginally significant reduction in total 24-hour energy intake, whereas 30 mg of sibutramine (positive control) was associated with a significant reduction in total 24-hour energy intake (48)
Previously, whether the elevated plasma level of triglyceride is causally associated with ASCVD has been controversial

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Yes, but dosage should be followed carefully

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