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Dysfunction of CI is a defining feature of circadian disruption and diet-induced obesity in adipose tissue, linking clock misalignment to visceral adipocyte hypertrophy, ectopic lipid deposition in liver and impaired glucose tolerance

A novel l-serine deaminase activity in Escherichia coli K-12

GPx7 likes to interact with the domain of PDI, and intramolecular cooperation between the two redox-active sites of PDI increases the activity of the Ero1/GPx7/PDI triplet, thereby promoting protein folding mechanisms (Wang et al., 2014) (Figure 6)

This restores the function of the methylmalonyl-CoA mutase enzyme, allowing the seamless conversion of methylmalonyl-CoA into succinyl-CoA