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Because cuproptosis preferentially targets cells with high oxidative phosphorylation (OXPHOS) dependency, whereas glycolytic tumors remain relatively resistant, it exposes a distinct metabolic vulnerability in cancer and presents unique therapeutic opportunities 165,166
doi: 10.1101/gad.466308 101 UhlenM.OksvoldP.FagerbergL.LundbergE.JonassonK.ForsbergM.et al
10.1016/j.foodchem.2022.133997 44 EbelB.MartinF.LeL
Shanbhag et al., 2020
Plasma vitamin E level was determined by method of Catignani (24) with slight modification
