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(A) 2 hours (h), (B) 6 hours, and (C) 12 hours after the last challenge with OVA, the AR was recorded

TLR3 detects double-stranded RNA (dsRNA) [21], TLR7 and TLR8 recognise single-stranded RNA (ssRNA) [22], and TLR9 is activated by DNA containing unmethylated CpGs which are abundant in microbial but rare in vertebrate genomes (i.e., 6090% of mammalian CpGs are methylated) [23,24]

Laboratory research

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