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The expression of the two genes encoding the enzyme of the second step of glutathione synthesis (GSHS) in the cytosol and chloroplast increased with increasing light intensity, and this change was accompanied by an increase in total glutathione contents in these cell compartments

For instance, hypermethylation of the gene promoter in the KEAP1/NRF2 axis has been described in various tumor tissues and is closely related to tumor recurrence and drug resistance (128130)

The molecular targets and therapeutic uses of curcumin in health and disease , 105-125

Conclusion Our synthesis of the published findings indicates a notable overlap between results from both animal models and humans which could show a potential usage of mitochondrial-related targets as biomarkers or for drug discovery

Structural organization of the human selenium-dependent phospholipid hydroperoxide glutathione peroxidase gene (GPX4): chromosomal localization to 19p13.3