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doi: 10.1038/nrdp.2018.1 4 KaulAGordonCCrowMKToumaZUrowitzMBvan VollenhovenRet al

Signal integration is accomplished by the assembly of cytosolic pattern recognition receptors (PRRs), including nucleotide oligomerization domain (NOD)-like receptor (NLR) family pyrin domain containing 1 (NLRP1), NLRP3, NLRC4, absent in melanoma 2 (AIM2), and pyrin, and activation of caspase-1

AP-1 function and regulation

Abnormal early cleavage events predict early embryo demise: sperm oxidative stress and early abnormal cleavage

Meet BPC-157, TB-500 and CJC-1295, to name a few, which sound like pseudonyms straight out of a sci-fi script but are actually loosely regulated injectable peptides that are becoming part of a broader self-optimisation movement