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[DOI] [PMC free article] [PubMed] [Google Scholar] 61.Lagoumintzis G., Afratis N.A., Patrinos G.P

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Increased levels of ROS are accompanied by activation of the antioxidant system, further enhancing drug resistance ( 3.6.5 Redox regulation DTP cells survive drug-induced oxidative stress by increasing the expression of enzymes such as glutathione peroxidase 4 (GPX4) and aldehyde dehydrogenase (ALDH), scavenging harmful substances generated by oxidative stress, and maintaining intracellular redox balance ( In summary, these differences provide different targets and ideas for therapeutic strategies against DTP cells and LSCs

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Model-based metabolic engineering enables high yield itaconic acid production by Escherichia coli

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Healthy adults who drink 12 ounces of sugar-sweetened soda beverages per day may have accelerated aging as evidenced by shorter telomeres

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