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doi: 10.1155/2022/3403009 48 LuoMWuLZhangKWangHZhangTGutierrezLet al

Combining X-ray crystallography and in silico predictions with biochemical and cellular analysis, we reveal that Retromer directly associates and recruits the RAB10 regulators DENND4A, DENND4C, TBC1D1, and TBC1D4, and the RAB35 regulator TBC1D13 to regulate retrieval sub-domain function

[PubMed: 26608256] 166

GSH The Reduced Form of Glutathione This is what most people mean when they say glutathione

Our findings suggest that combining computational and in vitro new approach methodologies (NAMs) informed by adverse outcome pathways (AOPs) associated with pulmonary toxicity can provide relevant biological coverage for chemical lung safety assessment