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Alveolar fluid glutathione deficiency in patients with pulmonary edema or respiratory distress (ARDS) linked to Covid-19, has been shown to correlate with increased damage and inflammation of mediated lung cells by ROS ( Reactive Oxygen Species )

wherein R114 is substituted with either an A, C, D, E, F, G, H, I, K, L, M, N, P, Q, S, T, V, W, or Y