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Despite its significant potential, GO faces significant challenges, including scalability limitations, long-term stability concerns, and reproducibility/regeneration issues, which have been addressed with possible solutions, including health concerns for its sustainable futuristic applications.

Notably, this article proposes a new perspective: lactate accumulation in certain tumors may constitute an adaptive metabolic strategy rather than a passive consequence of altered metabolism

It is particularly prominently represented in our liver, as the main detoxification organ

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