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Activation of the NRF2 pathway, including induction of NAD(P)H:quinone oxidoreductase 1 (NQO1) and heme oxygenase-1 (HO-1), promotes autophagic clearance and restrains over-activation [87] (Fig

This in turn doubles the capacity of the available growth factors to promote signaling cascades necessary for cell development and regeneration

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In addition, overexpression of miR-296 is also associated with the disease and causes thyroid cell enlargement (Pu And Zhang 2024)

Biochemistry 62(3):851862