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Half of the normal saline A hypotonic crystalline solution has a lower concentration of solutes than plasma (half the concentration of chloride) unlike normal saline, which is an isotonic solution, treats patients with renal dehydration and loss of gastric fluids, and is suitable for diabetics who cannot tolerate additional glucose, and is not given to patients Burns, liver disease or trauma

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These studies suggested GSTM2 regulated lipid metabolism specially beyond detoxification/antioxidant, the basic functions of GSTs

doi: 10.1016/j.jnutbio.2020.108523 71

However, COX-2 is also expressed in the kidney, and whether COX-2 inhibitors truly offer a safer overall profile in patients with cirrhosis remains an open question