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Glutamines role in cellular functions makes GLS inhibition an ideal candidate for combination therapy

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1 With the advent of APAP/opioid combination analgesics and the ever-growing number of prescription narcotics being prescribed by medical practitioners, a larger number of patients have been placed in harms way as they are at significant risk of APAP hepatotoxicity

[7] Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene

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