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these observations corroborate the notion that specific subtle constraints must exist whereby a particular G6PD variant has a distinctly severe clinical expression but remains compatible with life

Protein science : a publication of the Protein Society , 6 (10), 21802187

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Alam S, Li Z, Janciauskiene S, Mahadeva R

However, the results of our present study showed that SNAP can not suppress ferroptosis induced by BSO alone (data not shown), but it still exhibits a quite strong protection against ferroptosis jointly triggered by glutamate or erastin + BSO (used at a very low concentration)