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SARS-CoV-2 proteins could sense the host cellular metabolic status and accordingly trigger human metabolic reprogramming/dysregulation (HMRD) in the infected human host

Other manifestations associated with selected symptoms such as dry mouth, weakness, headaches, tremor, muscle and abdominal pain, fever/sweats/chills, and sleep disturbance were also recognized

Both types of cross-linking may be caused by depletion of the lens reduced glutathione and accumulation of LPO products in the lens tissue

Lastly, exercise has been reported to reduce the secretion of adipsin from BMAds, which interacts with OPN to stimulate bone resorption through mechanosensing mechanisms (452)

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