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Similar to that report, wild-type PGL-1 tagged with GFP also formed large cytoplasmic granules when expressed in mammalian cells (Fig

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This process seems to be important in mosquitoes defense mechanisms against the West Nile Virus and the Sindbis virus (205), Additionally, phagocytosis of apoptotic cells was found to impart defense against the Drosophila C virus (129)

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