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That made internal approval much easier for our pharmacy committee

We and others reported that the loss of OL in AD brain can be recapitulated in distinct transgenic mouse models carrying single ( APP (9)), double ( APP , PSEN1 (10)) and triple ( APP , PSEN1 , MAPT (1113)) genetic mutations associated with the amyloid cascade hypothesis

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In this paper, we consider as outcomes of interest the [GSH]/[GSSG] ratio and the model outputs for the concentration of NADPH, ROS and G6P at time points for which calibration and validation data measurements are available (PN12, PN13, PN15, PN17, PN28)

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