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Under normal conditions, Hcy concentrations in plasma and tissues are low (515 M) as a result of remethylation and transsulfuration pathways that are coupled to B-vitamin (B12, folate, B6) and betaine metabolisms 6,7,8

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[DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted] 7.Antoniades C.G., Quaglia A., Taams L.S

Then, 5 of 29 on the elderly, B-vitamins deficiency may manifest as mood disorders, behavioral disorders, autonomic dysfunction, polyneuropathy and encephalopathy (, )
