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The diagnostic process typically involves: Clinical history taking, focusing on symptoms (fatigue, neurological changes, dietary habits) Physical examination for signs of anaemia or neurological impairment Blood tests including full blood count, serum B12, and often folate levels Additional investigations such as intrinsic factor antibodies or parietal cell antibodies if pernicious anaemia is suspected For borderline results, additional tests like holotranscobalamin (active B12) may be considered NICE guidance recommends that treatment should commence based on clinical presentation if neurological symptoms are present, without waiting for laboratory confirmation, as delays can result in irreversible nerve damage

10.1016/j.bcp.2024.116250 206 ZhangJ

Collagen peptides taken orally support connective tissue repair without the angiogenic concerns associated with injectable regenerative peptides

This is the nearest human data in the class, and it was negative which is context for efficacy, not evidence that Dihexa is unsafe or safe

Copper Peptides in Dermal Repair and Skin Regeneration